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NCL News Archive
Wednesday, November 1, 2017
Characterization of Nanoparticles Intended for Drug Delivery
The NCL has recently published a follow-on book to its Characterization of nanoparticles intended for drug delivery. This second edition book, now available for download or purchase, offers new and updated protocols for sterility and endotoxin testing, surface coating quantitation, ICP-MS of biological matrices, in vitro hematotoxicity and immunotoxicity, as well as in vitro methods for... View Post
Wednesday, November 1, 2017
New Protocols for Surface Characterization
Two new protocols for surface characterization have been published on the NCL Assay Cascade Protocols webpage.
PCC-16 describes PEG quantitation for PEGylated colloidal gold nanoparticles using reversed phase high performance liquid chromatography (RP-HPLC) and charged aerosol detection (CAD). Two different techniques are described in the protocol, and provide a means to quantitate... View Post
Monday, July 10, 2017
New Drug Release Protocol Available
The NCL has just added a new protocol to our Assay Cascade Protocols page to measure drug release from nanomedicines. The protocol, PHA-2, is based off of the recent Journal of Controlled Release publication, Stable isotope method to measure drug release from nanomedicines. Since its publication in late 2015, this assay has gained a lot of attention and has been in high demand at the NCL,... View Post
Monday, July 10, 2017
Inaugural FNLCR Technology Showcase Draws Hundreds
More than 200 science and business professionals from across the region attended the Frederick National Laboratory for Cancer Research’s (FNLCR) Inaugural Technology Showcase event. The program highlighted technologies developed by NCI and FNLCR investigators available for license or other collaborative development. In addition, Frederick city and county officials highlighted partnership... View Post
Wednesday, May 3, 2017
Nanomedicine Award 2017
The European Technology Platform for Nanomedicine (ETPN) and the EU-funded consortium ENATRANS have launched the third edition of the Nanomedicine Award to honor the best international nanomedicine innovations for 2017.
The goal of the Award is to promote and reward two excellent innovative nanomedicine-based solutions that could bring significant benefits to patients, answering unmet... View Post
Wednesday, May 3, 2017
New Innovative Research in Cancer Nanotechnology (IRCN) Funding Opportunity Announcement (R01)
NCI’s Office of Cancer Nanotechnology Research has published a new funding opportunity announcement (FOA) for the Innovative Research in Cancer Nanotechnology (IRCN) initiative, PAR-17-240. All IRCN awards made through this announcement are R01 grants and will be part of the Alliance for Nanotechnology in Cancer network. Due dates are twice per year, with the announcement remaining open until... View Post
Tuesday, April 4, 2017
2017 FNLCR Technology Showcase
The Frederick National Laboratory for Cancer Research (FNLCR) will be hosting a half-day event that will showcase technologies being developed at the National Cancer Institute (NCI) and FNLCR. The event aims to introduce the Frederick community to the regional technology development stakeholders, highlight available resources, as well as to encourage startup company formation, technology... View Post
Friday, March 3, 2017
Equivalence of Complex Drug Products: Scientific and Regulatory Challenges
Missed the NYAS meeting on “Equivalence of Complex Drug Products: Scientific and Regulatory Challenges”? The academy has just published an e-briefing from the meeting. Here you will be able to find notes from the meeting, as well as videos of select presentations. You can also find links to related publications and websites.
The meeting was co-organized by the Non Biological... View Post
Thursday, February 2, 2017
Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions.
The first issue of ACS Nano for 2017 features an article on the “Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions.” The article, co-authored by NCL’s Senior Immunologist, Marina Dobrovolskaia, along with several other well-known names in the field, summarizes the topics of discussion from a recent meeting on the subject. The two-day workshop was held... View Post
Tuesday, December 6, 2016
Nature Reviews Materials
NCL’s Director, Scott McNeil, recently published a Correspondence article in Nature Reviews Materials. “Evaluation of nanomedicines: Stick to the basics”, was written in response to another recent Nature Reviews Materials article, Wilhelm, et al, Nature Reviews Materials, 2016, 1, 16014. The Wilhelm, et al. article provides a retrospective analysis of nanoparticle drug... View Post